Is It Safe To Consume Flexeril And Ibuprofen Together?

Ask your doctor before making any changes in how or when you take your medications. Eight double-blind controlled clinical studies were performed in 642 patients comparing FLEXERIL 10 mg, diazepam, and placebo. Muscle spasm, local pain and tenderness, limitation of motion, and restriction in activities of daily living were evaluated. In three of these studies there was a significantly greater improvement with FLEXERIL than with diazepam, while in the other studies the improvement following both treatments was comparable.

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One of the most common drugs that interact with muscle relaxers or spasmolytic agents includes painkillers. The former works by inhibiting the afferent nerves from releasing excitatory neurotransmitters, thereby producing sedative effects. Likewise, based on a study by a medical doctor from England, painkillers work by inhibiting excitatory neurotransmitters. Since these drugs both slow down the CNS, they both induce depression. Eventually, when taken together, they can cause difficulty of breathing and loss of consciousness. They belong to two different drug classes – muscle relaxant and benzodiazepine, respectively.

Side Effects

Cyclobenzaprine caused slight to moderate increase in heart rate in animals. Flexeril is a muscle relaxer drug, while Ibuprofen is an anti-inflammatory drug. These two medications- Flexeril and Ibuprofen, don’t show any interactions. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely used to alleviate pain, reduce inflammation, and lower fever. It belongs to a class of medications known for their analgesic and anti-inflammatory properties. Ibuprofen is commonly used for various conditions, including headaches, toothaches, menstrual cramps, and mild to moderate musculoskeletal pain.

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Of course, we can’t say that there’s a 100% safe drug (or drug combination) out there. However, the gist here is that these two are considered generally safe to be taken together. Plus, there are no reports of major interactions between them.

For a thorough understanding of potential side effects, please consult a physician. Another rare side effect is an allergic reaction to the drug, manifested by hives and trouble breathing. To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.

What happens if I overdose on Cyclobenzaprine (Flexeril)?

As of 2019, there are around 1,000 drug interactions with this medication and these include muscle relaxants. Zoloft interactions with these drugs increase the risk of quite a health condition known as Serotonin Syndrome. The symptoms of this syndrome include seizures, hallucinations, increased heart rate, fever, spasms, nausea, cramps, in-coordination, and diarrhea. Flexeril is a medication belonging to a class of skeletal muscle relaxants used to treat muscle spasms.

However, it is only for short-term relief from acute muscle pain and other skeletal conditions. It works by directly reducing muscle hyperactivity and decreasing the transmission of pain. In a study of healthcare professionals from New York, it was reported that weed is an effective substance to treat lower back pain. However, when abused, using these drugs together with cannabis increases side effects such as drowsiness, confusion, dizziness, and difficulty in concentrating. Due to harmful muscle relaxers interactions with CBD, an individual can experience impairment in thinking and judgment. Alcohol is known to produce some pain-relieving effects, but taking these drugs at the same time with antispasmodics is not advised as this combination can increase CNS depression.

• In these cases, your doctor may want to change the dose, or other precautions may be necessary.
• Flexeril and ibuprofen can provide a more comprehensive approach to managing back pain when used together.
• According to the US Food and Drug Administration, drug interactions occur when two or more drugs are taken together.
• Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants) concomitantly with MAO inhibitor drugs.
• All in all, you’ll want to stop cyclobenzaprine in 2–3 weeks and rely on physical therapy sessions to control the pain in the long term.

It is also much more addictive than conventional painkillers or Over-the-counter (OTC) Non-Steroidal Anti-inflammatory Drugs (NSAIDs) available in the market that are pain relievers in action. It is not controlled under the Controlled Substances Act (CSA), either. However, since Flexeril has properties that suppress pain, flexeril.live people may overuse it to amplify those feelings. The activity of Flexeril that depresses the Central Nervous System (CNS) makes it potentially addictive and dangerous. This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so.

Ask your doctor when to start or stop taking this medication. Drowsiness, dizziness, dry mouth, constipation, or tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

According to medical doctors from the USA, these drugs are used for the treatment of anxiety disorders, insomnia, epilepsy, seizure disorders, and agitation. In rare cases, benzodiazepines are used to relieve spasticity and pain due to various neurological disorders such as spinal cord injury and strokes. But if someone mixes them with muscle relaxers, the individual becomes prone to face many muscle relaxers interactions. One of the dangerous interactions includes the increase in the severity of CNS depression. In this section, information about some of these benzodiazepines that may interact with these drugs will be discussed.